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Higher levels of hs-CRP are associated with the risk of PsA development in patients with psoriasis1

Based on a study by Eder L et al. presented at ACR 2023.

Published on

07 Jun 2024

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*p=0.003, p<0.001 and p=0.004 for patients with arthralgia, obesity (BMI >30) and female patients, respectively.1 

Data were analysed from a prospective cohort of 589 patients with psoriasis without PsA at enrollment from 2006–2019. hs-CRP values were measured at baseline using standard commercial assays in a hospital laboratory. All patients (n=589) had hs-CRP measurements at baseline; n=35 received biologic therapy at baseline; n=272 had nail lesions at baseline. Patients were assessed annually by a rheumatologist for signs and symptoms of PsA.

BMI: body mass index; hs-CRP: high-sensitivity C-reactive protein; PsA: psoriatic arthritis; SD: standard deviation. 

1. Eder L et al. Arthritis Rheumatol. 2023;75(suppl 9). Abstract 0484. 2. Gottlieb AB, Merola JF. J Dermatolog Treat. 2022;33(4):1907–1915.