How relevant is the IL-17 family to SpA pathobiology?

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How relevant is the IL-17 family to SpA pathobiology?

Watch Prof. Lars Erik Kristensen and Prof. Frank Behrens discuss the role of the IL-17 family of cytokines in SpA pathobiology:

Prof. Kristensen and Prof. Behrens highlighted the following key takeaways on the IL-17 family in SpA. To dive deeper, play their bitesize short 2-minute interviews above!

Prof. Kristensen notes the complexity of SpA pathobiology, with many different cytokines involved. Of these, the IL-17 family plays a key role in SpA pathobiology, including independent roles for IL-17F and IL-17A.^1,2

Prof. Behrens highlights that IL-17A and IL-17F may have different roles in inflammation at different timepoints.²

Published on

10 Nov 2023

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IL: interleukin; SpA: spondyloarthritis.

1. Taams LS et al. Nat Rev Rheumatol. 2018;14(8):453–466. 2. Cole S et al. J Allergy Clin Immunol. 2023;152(3 Suppl 7):783–798.

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